Acalypha indica induced hemolytic crisis and methemoglobinemia in G6PD deficiency

Phenazopyridine-induced hemolytic anemia in a patient with G6PD deficiency.

Methemoglobinemia and intravascular hemolysis in a patient with G6PD deficiency.

Modelling primaquine-induced haemolysis in G6PD deficiency

Primaquine is the only drug available to prevent relapse in vivax malaria. The main adverse effect of primaquine is erythrocyte age and dose-dependent acute haemolytic anaemia in individuals with glucose-6-phosphate dehydrogenase deficiency (G6PDd). As testing for G6PDd is often unavailable, this limits the use of primaquine for radical cure. A compartmental model of the dynamics of red blood c...

Antibacterial activity of Acalypha indica L.

Hexane, chloroform, ethyl acetate and methanol extracts from the leaves of Acalypha indica were tested against Gram-positive (Staphylococcus aureus, Staphylococcus epidermidis, Bacillus cereus, Streptococcus faecalis) and Gram-negative (Klebsiella pneumoniae, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa) bacteria. All the extracts exhibited antibacterial activity against Gram-posi...

Identification and Quantification of Phytocompounds in Acalypha Indica Leaves

Acalypha indica, a known medicinal plant in the treatment of various degenerative diseases and a potential source of valuable bioactives. The present study investigates the total phenolic and flavonoid content and also screen for phytocompounds in A. indica leaf extract obtained by two extraction methods, comparatively. Results indicated that the maceration extraction method (MEM) had highest t...